HOW PRAXBIND WORKS:

An Immediate and Specific Reversal Agent for PRADAXA

  • PRAXBIND specifically binds to dabigatran and its acylglucuronide metabolites, neutralizing their anticoagulant effect immediately after administration
  • Binds with higher affinity than dabigatran to thrombin
  • Has no effect on other anticoagulant or antithrombotic therapies

Immunogenicity

  • Low potential for immune reactions

    • 4% of volunteers showed low concentrations of treatment-emergent antibodies that may persist
Video: How PRAXBIND Works
Watch a video about how PRAXBIND works

This brief video reviews how PRAXBIND reverses the anticoagulant effect of dabigatran.